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Combining the advantages of highly evolved Natural Products with parallel chemistry for efficient drug discovery, these unique three-dimensional chiral scaffolds with decorated pharmacophore functionalities together with the potential for scale-up chemistry will complement and enhance your screening libraries.
AnalytiCon Discovery offers its unique semi-synthetic screening compound libraries, which make use of nature’s diversity, for application in the pharmaceutical, cosmetic and agro-chemical industries. The NatDiverse™ concept which is used starts with a selected pure Natural Product – available for AnalytiCon on a kilogram scale – and ends up with lead-like structures for biological screening which show a high potential for further development due to their compatibility with medicinal chemistry. The underlying templates are chemical entities with biological pre-validation. The design of the final compounds employs Lipinski and Veber rules, known and unusual pharmacophore groups and straightforward follow-up chemistry for further hit-to-lead optimization programs.