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AnalytiCon´s R&D pipeline consists of different drug discovery projects with major focus on oncology, metabolic, and infection diseases.
The following preclinical projects are available for collaboration or licensing:
Cancer Research Projects
Diabetes Research Projects
For more information please contact: info@ac-discovery.com.
AnalytiCon Research Technologies derived from our projects are also available separately.
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Assay format: | Biochemical / 96 well MTP | |
| Read out: | Fluorescence kinetic | ||
| Enzyme: | Human or rat serum DPPIV | ||
| Applications: |
High throughput screening IC50 determination Pharmacodynamics (ex vivo) Enzyme kinetics (MoA) Reversibility test Bioassay-guided fractionation |
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| Track record: | DPPIV inhibitors (ACD-0806 and ACD-0807) were revealed from edible biomaterials by means of the assay system.* |
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| Price: | 5,50 € / well |
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Assay format: | Biochemical / 96 well MTP | |
| Read out: | Absorbance kinetic | ||
| Enzyme: | Rec. human PTP1B | ||
| Applications: |
High through-put screening IC50 determination Enzyme kinetics |
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| Track record: | Discovery of novel PTP1B inhibitors (ACD-0811, ACD-0820, and ACD-0825) by means of medium throuput screening (MTS) was observered.* |
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| Price: | 4,50 € / well |
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Assay format: | Db/db mice feeding study with special diets | |
| Read out: |
Body weight Food intake Plasma glucose Active GLP-1 DPPIV activity 8-Isoprostane Hemogram |
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| Track record: | Discovery of novel Natural Products (ACD-0831 (Group 3) and ACD-0834 (Group 4)) modulating body weight gain in hyperphagic, diabetic db/db mice.* |
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| Price: | On request |
For more information please contact: info@ac-discovery.com.
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EUROPÄISCHE UNION Europäische Fonds für regionale Entwicklung Investition in Ihre Zukunft www.efre.brandenburg.de |
and the Brandenburg Department of Commerce www.wirtschaft.brandenburg.de